Diet: Vitamin A May Help in Fight Against Tuberculosis

matteo_vitamin AResearchers at the University of California, Los Angeles believe that increasing the active form of vitamin A (known as all-trans reinoic acid) in cells helps them combat tubercle bacillus (TB), more commonly known as tuberculosis. Their work shows that TB feeds on cholesterol found in parts of cells called lysosomes. When exposed to greater amounts of active vitamin A, cholesterol levels in these organelles decrease. Not only does this cut TB off from a nutritional source but it also appears to stimulate the cell to defend itself from infection. Experts classify tuberculosis as a major global health problem that’s responsible for an estimated two million deaths each year.
Immunology, March 2014